In as we speak’s health-conscious world, dietary dietary supplements have turn into a well-liked instrument for filling dietary gaps, enhancing general well-being, and even managing particular well being circumstances. Nonetheless, not all dietary supplements are created equal. Some will be contaminated, work together with medicines, and even hurt liver well being. Choosing the proper complement requires cautious consideration and consciousness of potential dangers, and it additionally means being conscious of shady advertising ways!
‘Dietary supplements’ is an umbrella time period for supplemental types of particular person vitamins like calcium and iron. However the extra problematic of the bunch are ‘pure’ dietary dietary supplements which are marketed with shady claims, proprietary formulation, and little to no testing. These are the kinds of dietary supplements that I’m largely referring to on this put up.
The Hidden Risks of Dietary supplements: Liver Failure, Latest Analysis, and Learn how to Keep Secure
Dietary dietary supplements are a multi-billion-dollar trade, marketed as a straightforward manner to enhance well being, improve vitality, and fill in dietary gaps. Nonetheless, behind the shiny labels and well being claims, a rising physique of analysis reveals that some dietary supplements can pose severe well being dangers—together with liver failure.

In recent times, circumstances of supplement-induced liver harm (SILI) have been on the rise, with sure natural and dietary dietary supplements linked to extreme liver injury, hospitalization, and even demise. Regardless of being broadly obtainable over-the-counter and infrequently perceived as “pure” and protected, many dietary supplements are poorly regulated and may comprise dangerous components.
Complement Advertising and marketing is a Dumpster Fireplace
‘However it’s pure!’ So are toxic mushrooms, however no person desires to eat these. The complement trade – specifically the diet complement trade – is constructed on convincing individuals to purchase dietary supplements that we really don’t want.
Implying that dietary supplements are extra ‘pure’ than medicines works on the Attraction to Nature fallacy, which complement makers use to make their product seem safer than prescription drugs. As a dietitian, I’m seeing this rather a lot with GLP-1 dietary supplements, that are largely simply rubbish. Nothing about them is efficient or safer than precise medicines, that are regulated and prescribed below managed circumstances (ideally…everyone knows one thing who’s getting them from doubtful sources).
I used to be unreasonably completely satisfied to see that Kourtney Kardashian’s Lemme GLP-1 complement is at the moment the topic of a category motion lawsuit for claiming to work like GLP-1 agonist medicine. It doesn’t. However as I wrote in one in all my latest posts, there are lots of individuals who need GLP-1 medicine however can’t afford it. This leaves a niche that’s being grossly exploited by the complement trade.


That’s how shady complement makers earn their cash, and it typically works…to the tune of $177 billion {dollars} in 2023, and projected to develop exponentially for the forseeable future. Whether or not it’s weight reduction, menopause, blood sugar (see my Glucose Goddess Anti Spike overview right here), immunity-boosting, or no matter else, the complement trade has a capsule for that.
It goes with out saying that if a complement is claiming to remedy anxiousness or despair or some other psychological well being prognosis, it’s an enormous crimson flag. Claims like these are unethical and probably harmful, as they’ll persuade individuals to desert efficient and obligatory medicine.
Getting clever to complement advertising scams takes just a few small checks.
Diet Complement Crimson Flags:
No analysis, or basing claims on animal or cell analysis. Even when you aren’t well-versed in studying analysis, at all times check out the complement’s web site to see if it presents analysis to again up its claims. Is the analysis performed on people? Animals? How previous are the research? Is the analysis performed on the product itself, or solely on sure components that the product comprises?
I wrote a put up about the fundamentals of decoding diet analysis right here, however the TL;DR is that you really want latest research (as in, final 5 years), performed in people, printed in peer-reviewed journals, on the product itself. 99% of the time, you received’t discover all of these issues. That could be a crimson flag.
Something offered by multi-level advertising. Not solely do MLM corporations prey on weak individuals (primarily girls), they have a tendency to take advantage of egregious claims about their merchandise. MLM salespeople aren’t skilled to provide diet recommendation or perceive your well being historical past. Belief me – if one thing groundbreaking exists, it will likely be regulated by the FDA and offered in drugstores, not by some MLM coach.


Implying that their system was found by ‘Harvard (or X Ivy League) scientists’ or that Massive Pharma/precise scientists haven’t but found this groundbreaking secret. I see this rather a lot from corporations like VShred (learn my VShred overview right here) and Lifevantage (learn my Lifevantage Protandim and GLP-1 overview right here), amongst many others. There isn’t any large secret. No person is hiding something (moreover these corporations attempting to cover their grift, though they aren’t fooling me!). Identify dropping an Ivy League faculty by no means means something, both. It’s all bluster created to provide them false legitimacy.
Claiming {that a} complement can remedy the incurable, corresponding to autism, ADHD. Don’t even go there.
Massive claims and use of statistics that appear too good to be true. 95% of individuals love this complement? How did the corporate even decide that? Trace: they didn’t.


Using earlier than and after pictures and testimonials to ‘show’ efficacy of a product. These are simply faked, and so they present up when an organization has nothing higher to supply when it comes to proof of their product working.
The declare of being safer, extra pure, or equally efficient as precise medicines. We talked about this above.


Imprecise claims utilizing phrases or phrases like ‘helps metabolism’ or ‘helps with X’. That is how corporations could make the claims they make, with out triggering the FDA’s consideration. It’s a loophole that many individuals don’t learn about, however now you do!
Using influencers to promote the product. This one could be controversial, however I really feel like widespread influencers utilizing affiliate codes to flood peoples’ social feeds with adverts for a product is a distraction and made to persuade potential prospects that in the event that they use the product, they’ll be younger/engaging/wholesome/widespread just like the individuals promoting it.
The Risks of Diet Dietary supplements
Whereas all diet dietary supplements are marketed as helpful, they’ll typically do extra hurt than good. A few of the key dangers embrace:
Lack of Regulation
The U.S. Meals and Drug Administration (FDA) regulates dietary supplements below the Dietary Complement Well being and Schooling Act (DSHEA) of 1994, which permits producers to promote merchandise with out proving their security or efficacy. In contrast to pharmaceuticals, dietary dietary supplements aren’t required to endure rigorous testing earlier than hitting the market.
Which means that:
Dietary supplements might comprise unlisted or dangerous components.
Dosages could also be inconsistent or increased than beneficial.
Contaminants corresponding to heavy metals, pesticides, or pharmaceuticals could also be current.
The FDA sometimes doesn’t get entangled until there has really been hurt performed to an individual by the complement.


Liver Toxicity and Organ Injury
The liver performs an important function in processing dietary supplements, breaking down compounds, and detoxifying dangerous substances. Nonetheless, sure dietary supplements comprise components that may overwhelm or injury liver cells, resulting in:
Hepatotoxicity (liver toxicity): The liver struggles to course of poisonous compounds, resulting in irritation and cell injury.
Acute liver failure: Extreme circumstances the place the liver loses its capacity to operate, typically requiring a transplant or leading to demise.
Power liver illness: Lengthy-term injury from repeated publicity to dangerous dietary supplements.
Harmful Interactions with Medicines
Many individuals take dietary supplements alongside prescription medicines with out realizing that sure mixtures will be poisonous.
For instance, St. John’s Wort can scale back the effectiveness of antidepressants and contraception capsules. Kava and inexperienced tea extracts have been linked to extreme liver injury, particularly when taken with different medicines metabolized by the liver. Vitamin A and iron in extreme doses could cause liver irritation and injury.
Latest Analysis on Complement-Induced Liver Failure
Over the previous decade, scientific research and medical stories have highlighted a regarding rise in supplement-related liver harm.


The DILIN Examine (2014 – Current)
The Drug-Induced Liver Harm Community (DILIN), a U.S.-based analysis initiative, has been monitoring circumstances of drug- and supplement-related liver harm.
Their findings present that:
Natural and dietary dietary supplements account for 20% of liver harm circumstances within the U.S.
The speed of supplement-induced liver injury has elevated from 7% in 2004 to twenty% lately.
Weight-loss and bodybuilding dietary supplements are probably the most generally implicated.
Inexperienced Tea Extracts and Hepatotoxicity
Inexperienced tea extract is a well-liked complement discovered in lots of weight-loss merchandise, however analysis has linked it to extreme liver toxicity.
A 2018 examine within the journal Hepatology discovered that catechins, the energetic compounds in inexperienced tea, could cause liver injury in excessive doses. Some circumstances resulted in acute liver failure requiring transplants. A 2022 examine discovered garcinia cambogia, with or with out inexperienced tea (I’ve seen numerous dietary supplements that comprise each of those components) could cause reasonable to extreme liver harm.


Bodybuilding Dietary supplements and Undisclosed Steroids
Bodybuilding dietary supplements are among the many most harmful, with many containing undeclared anabolic steroids that may trigger liver toxicity.
A 2017 examine in The Journal of Gastroenterology and Hepatology discovered that:
Practically 50% of liver harm circumstances in younger males have been linked to bodybuilding dietary supplements.
Many of those dietary supplements contained unlawful or undisclosed steroid compounds.
Heavy metals like arsenic, micro organism and fungi, banned stimulants like ephedrine, and undeclared medicine like sibutramine (discovered to have cardiac dangers) are only some examples of what has lately been present in natural diet dietary supplements.
Whereas not all dietary supplements are dangerous, it’s important to strategy them with warning. Right here’s find out how to shield your self:
Do Your Analysis Earlier than Taking Any Complement
Search for scientific research that help the protection and effectiveness of a complement.
Be skeptical of merchandise that promise speedy weight reduction, excessive muscle acquire, or “detox” advantages. If one thing is promising to do what no different complement or medicine has performed earlier than (ie fats burners), stroll or scroll proper on by. Whereas a complement won’t be harmful, I additionally take into account the monetary impacts of taking something you don’t actually need.


Select Third-Social gathering Examined Dietary supplements
Because the FDA doesn’t regulate dietary supplements strictly, search for third-party testing from organizations corresponding to:
U.S. Pharmacopeia (USP)
NSF Worldwide
ConsumerLab
These certifications make sure that dietary supplements comprise what they declare and would not have dangerous contaminants.
Keep away from Excessive-Danger Dietary supplements
A few of the most harmful dietary supplements embrace:
Inexperienced tea extract (excessive doses)
Kava
Kratom
Bodybuilding dietary supplements with steroids
Weight-loss dietary supplements with “fats burners” or stimulants
Discuss to Your Physician Earlier than Utilizing Dietary supplements
In case you are on medicines, ask your physician about attainable complement interactions.
When you’ve got liver illness, diabetes, or coronary heart circumstances, be further cautious with dietary supplements.
In Quick:
Dietary dietary supplements will be useful in some circumstances, however additionally they pose important dangers—particularly to liver well being. With analysis linking sure dietary supplements to liver failure, it’s essential to learn and selective about what you are taking.
By selecting third-party examined merchandise, avoiding high-risk dietary supplements, and prioritizing entire meals, you may shield your liver and general well being. At all times seek the advice of with a healthcare skilled earlier than including any new complement to your routine.
Your well being is value greater than a fast repair—keep knowledgeable, and keep protected!